Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced99mTc

Uncertainties in internal dose calculations for radiopharmaceuticals.

This paper presents a systematic analysis of the inherent uncertainty in internal dose calculations for radiopharmaceuticals. A generic equation for internal dose is presented, and the uncertainty in each of the individual terms is analyzed, with the relative uncertainty of all terms compared. The combined uncertainties in most radiopharmaceutical dose estimates will be typically at least a fac...

Comparison of the Absorbed Dose for 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Ethylenedicysteine Radiopharmaceuticals using Medical Internal Radiation Dosimetry

The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid ((99m)Tc-EC and (99m)Tc-DTPA) kidney scan. Patients who had been prepared for the kidney scan, were divided into two groups (Groups 1 and 2). The first group (Group 1) and the second group (Group 2) recei...

Assessment of radiation dose in nuclear medicine hot lab

Background: Hot lab is a specially designed room in a nuclear medicine hospital where the radiopharmaceuticals are delivered, stored and prepared for dispensing. 99Mo/99mTc-generator is the major source in the hot lab used for various medical imaging. It is important to maintain a standard for hot lab procedures to optimize the patient care and minimize radiation exposure to all nuclear medicin...

Optimization of Radiation Dose in Cranial Computed Tomography among Adults: Assessment of Radiation Dose against Image Quality

Introduction: The rapid use of computed tomography (CT) scan is of great concern, due to increase in patients’ dose. Optimization of CT protocol is a vital issue in dose reduction. This study aimed to optimize radiation dose in cranial CT and assess modifications in image quality under radiation dose reduction. Material and Methods: A poly(me...

From the Medical Internal Radiation Dose Committee.